HSP40 COUPLES WITH THE CSPALPHA CHAPERONE COMPLEX UPON INDUCTION OF THE HEAT SHOCK RESPONSE.

In response to a conditioning stress, the expression of a set of molecular chaperones called heat shock proteins is increased.In neurons, stress-induced and constitutively expressed molecular chaperones protect against damage induced by ischemia and neurodegenerative diseases, however the molecular basis of this protection is not known.Here we have

Hamsika Chandrasekar,1 Neil Gesundheit,2 Andrew B Nevins,3 Peter Pompei,4 Janine Bruce,5 Sylvia Bereknyei Merrell6 1Department of Pediatrics, Boston Children’s Hospital, Boston, MA, USA; 2Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, Stanford, CA, USA; 3Department of Medicine, Division of Infectiou